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WEBINAR | SENSOCELL: OPTICAL TWEEZERS FOR MECHANOBIOLOGY

WEBINAR | SENSOCELL: OPTICAL TWEEZERS FOR MECHANOBIOLOGY

Join Axiom Optics and Impetux for a demo of the SENSOCELL optical tweezers and force measurement platform.

📅DATE: March 12, 2021 | 10 AM PST / 1 PM EST | 7 PM CET 

 

SENSOCELL is an optical tweezers system with multiple trap generation capability including a force measurement module, and is designed for mechanobiology studies in living cells and 3D tissues.

During this webinar we will introduce the technology of optical tweezers, present the SENSOCELL platform and show some application examples including the latest data acquired with SENSOCELL.

We will conclude with an open Q&A session.

The webinar will last 45 minutes.

Who Should Attend this Webinar?

Scientists and researchers interested in mechanobiology studies, pattern morphing applications including organic or non-organic particles and liquid crystals, or just curious scientists interested in optical tweezing and manipulation of really tiny things.

A great opportunity to meet comfortably from wherever you want!

You can register here.

 

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Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Fig. 2

Force and displacement data for two beads stimulated at frequencies of 4 Hz and 0.25 Hz. The progressive reduction of the beads displacement is in concomitancy with an increase of the applied force and loading rate.

Fig. 1

Schematic representation of the optical tweezers experiment. A fibronectin-coated bead is trapped, brought into contact with the cell membrane and stimulated with oscillations at different frequencies.

Fig.2

Time dependence of trap 1 and trap 2 position (top) and force (bottom) data along the different steps of the described dual tether pulling experiment.

Fig.1

Confocal video of the described dual tether pulling assay performed on a neuron axon. Courtesy of M. Krieg lab (ICFO).

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Video 1

Confocal video showing a DVA neuron Ca2+ ion channel activity in a dynamic optical trapping assay. The pulling rate applied to the membrane tether is progressively increased. Scale bar = 5µm. Acquired at 10Hz.