Applications of SENSOCELL +
optical tweezers
SENSOCELL+ combines direct force measurements with fluorescence imaging and optional integrated high-speed confocal microscopy for correlated quantitative assays across molecular, cellular and soft-matter systems. Explore applications in mechanobiology, molecular biophysics, biomolecular condensates and soft matter physics.
From molecular interactions to living mechanics
Explore optical trapping applications across the systems you study, from individual molecules and biomolecular condensates to living cells, tissues and complex soft matter.
CELL MECHANOBIOLOGY
Forces, mechanics and interactions in cells, tissues and living organisms.
MOLECULAR BIOPHYSICS
Molecular interactions, motor proteins and cytoskeletal filaments.
Live-cell mechanics across scales
Measure membrane tension, intracellular mechanics and rheology, cell-cell interactions and force generation in living cells, tissues and organisms.
MEMBRANE TENSION & RECEPTOR FORCES
Measure membrane tension and receptor forces with automated tether pulling and particle-cell interaction assays.
NUCLEUS & SUBCELLULAR MECHANICS
Apply creep and stress-relaxation assays to probe nuclear and cytoplasmic mechanics inside living cells.
INTRACELLULAR RHEOLOGY
Quantify the viscoelastic properties of the cytoplasm, nucleus and other intracellular environments.
CELL-CELL INTERACTIONS
Measure immune cell binding forces with control over cell orientation and contact time.
CELL STIFFNESS & ELASTICITY
Indent cells to quantify the stiffness, elasticity and viscoelastic response of the cell membrane and cortex.
CELL FORCE DYNAMICS
Measure the forces generated by cells and the mechanical work they produce.
Measure forces and dynamics at the molecular scale
Use SENSOCELL+ to quantify molecular interactions, characterize cytoskeletal mechanics and resolve the activity of individual molecular motors through direct force measurements and correlated fluorescence imaging.
MOTOR PROTEINS & CYTOSKELETAL FILAMENTS
Measure motor protein activity and characterize the mechanics of cytoskeletal filaments and networks in vitro and inside living cells.
SINGLE-MOLECULE FORCE SPECTROSCOPY
Apply and measure forces in dual-trap and three-bead assays, from DNA stretching to individual myosin motor dynamics.
Follow condensates
mechanics as they age
Track changes in material state as phase-separated condensates form, fuse and age.
MECHANICS OF BIOMOLECULAR CONDENSATES
Quantify bulk and interfacial viscoelasticity through droplet fusion analysis and active microrheology.
Complex materials.
Their mechanics, simplified.
Explore how interactions and viscoelasticity govern the behavior of complex and active soft-matter systems.
COLLOIDS, GELS, BIOFILMS & ACTIVE MATERIALS
Measure interaction forces and complex shear modulus using automated force-probing and active microrheology workflows.
Is your application
not listed above?
If your application is not listed, discuss it directly with our scientists. We work with research teams to assess feasibility and define workflows.
