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IMPETUX at MBI 3M 2021

IMPETUX at MBI 3M 2021

IMPETUX at MBI 3M 2021

The next event in which IMPETUX will be present will be virtual and will be the conference: Materials, Mimics and Microfluidics: Engineering Tools for Mechanobiology (MBI 3M 2021) organized by the Mechanobiology Institute of the National University of Singapore.

If you are attending the event, join us at our exhibitor showcase talk:

SENSOCELL: A multiple optical trapping platform combining direct force spectroscopy & fluorescence imaging

📅DATE: Thursday 22th July at 1:00 PM (Singapore time)

We will show the advantages of our patented direct force spectroscopy technology and explain how we overcome the classical limitations of optical tweezers turning them into a high-level tool for mechanobiology.

You can head over to the event website to check out the complete program  here.

 

📌If you are interested in how our optical tweezers system: SENSOCELL can push your research forward in applications such as the measurement of cell membrane forces, the study of nucleus mechanics, the measurement of cell-cell interaction forces among others, do not hesitate to join us or contact us any time!

 

Time remaining before the start of this event:

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Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Fig. 2

Force and displacement data for two beads stimulated at frequencies of 4 Hz and 0.25 Hz. The progressive reduction of the beads displacement is in concomitancy with an increase of the applied force and loading rate.

Fig. 1

Schematic representation of the optical tweezers experiment. A fibronectin-coated bead is trapped, brought into contact with the cell membrane and stimulated with oscillations at different frequencies.

Fig.2

Time dependence of trap 1 and trap 2 position (top) and force (bottom) data along the different steps of the described dual tether pulling experiment.

Fig.1

Confocal video of the described dual tether pulling assay performed on a neuron axon. Courtesy of M. Krieg lab (ICFO).

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Video 1

Confocal video showing a DVA neuron Ca2+ ion channel activity in a dynamic optical trapping assay. The pulling rate applied to the membrane tether is progressively increased. Scale bar = 5µm. Acquired at 10Hz.