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IMPETUX at AQV days 2022

IMPETUX at AQV days 2022

Approches Quantitatives du Vivant

 

IMPETUX will participate at the conference: AQV DAYS 2022 : QUANTITATIVE APPROACHES TO LIVING SYSTEMS organized by the Institute Jacques Monod (France).

The conference is open to all members of the AQV network as well as to all researchers tackling biological questions with methods coming from physics, chemistry, engineering or other sciences.

 

The event will take place from 19 to 21 January 2022 (CEST)

The IMPETUX agenda will be as follows:

 

📅On Wednesday 19, at 16:45h.  we will be giving a talk to show the potential of an innovative instrument like SENSOCELL, the only optical trapping platform in the market combining multiple optical traps control at high speed with direct force spectroscopy enabling direct force measurements, even inside cells and tissues. In this occasion we will be focusing on applications like Cell membrane tension studies, Intracellular mechanics or micro-rheology inside cells.

📅On Thursday 20, at 14:30h. Severall SENSOCELL live demos will be carried out upon  previous time slot reservation at the Actin Dynamics Lab, the Guillaume Romet-Lemonne Lab at the Institute Jacques Monod

Join us and discover how to take further your research !

 

📌If you are interested in how our SENSOCELL optical tweezers system can help you in your Mechanobiology research projects check our applications page or contact us any time!

More news:

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Fig. 2

Force and displacement data for two beads stimulated at frequencies of 4 Hz and 0.25 Hz. The progressive reduction of the beads displacement is in concomitancy with an increase of the applied force and loading rate.

Fig. 1

Schematic representation of the optical tweezers experiment. A fibronectin-coated bead is trapped, brought into contact with the cell membrane and stimulated with oscillations at different frequencies.

Fig.2

Time dependence of trap 1 and trap 2 position (top) and force (bottom) data along the different steps of the described dual tether pulling experiment.

Fig.1

Confocal video of the described dual tether pulling assay performed on a neuron axon. Courtesy of M. Krieg lab (ICFO).

Fig. 1

Time dependence of trap position (top), force signal (middle) and Ca2+ fluorescence signal (bottom) recorded during a membrane tether pulling experiment. The force and Ca2+ ion channel activity signals exhibit negative correlation.

Video 1

Confocal video showing a DVA neuron Ca2+ ion channel activity in a dynamic optical trapping assay. The pulling rate applied to the membrane tether is progressively increased. Scale bar = 5µm. Acquired at 10Hz.