Applications of Sensocell optical tweezers

Our technology, allows scientists to probe forces and mechanics in living systems with unprecedented accuracy. Browse below to explore several key applications of optical tweezers in the fields of mechanobiology, molecular biophysics, liquid-liquid phase separation and soft matter physics. We work close with our customers to help them develop their specific applications. If you cannot find your specific field of study in this list, contact us and let’s discuss what we can do!

Home 9 Applications of optical tweezers

Cell Mechanobiology

cell membrane forces mechanobiology application

Membrane tension & receptor forces

Study the physical properties of membranes and membrane receptors via tether pulling and particle-cell interaction assays.

Cell nucleus mechanobiology

Subcellular mechanics

Apply creep & stress-relaxation tests inside cells and obtain the mechanical properties of the nucleus and the cytoplasmic medium.

cell elasticity application

Intracellular rheology

Measure the viscoelastic properties of the cytoplasm and other intracellular medium like the cell nucleus with our automatized active rheology routine.

cell cell interaction application

Cell-cell interactions

Establish cell-cell interactions and measure their binding forces while having absolute control on cells orientation and contact time.

cell membrane indentation application with optical tweezers

Cell indentation and stretching

Study how cells respond to mechanical stress by indenting or stretching cells and characterize their stiffness, elasticity, and viscosity.

Microswimmer cell motility mechanobiology application

Cell motility force dynamics

Measure the forces generated by and exerted on moving cells, and study the dynamics of cell motility.

Membrane tension & receptor forces

Investigate the physical characteristics of membranes and membrane receptors through tether pulling and particle-cell interaction experiments.

Subcellular mechanics

Conduct creep and stress-relaxation tests within cells to determine the mechanical properties of the nucleus and cytoplasmic environment.

Intracellular rheology

Assess the viscoelastic properties of the cytoplasm and other intracellular components, such as the nucleus, using our automated active rheology technique.

Cell-cell interactions

Establish and measure the binding forces in cell-cell interactions, with precise control over cell orientation and contact duration.

Cell indentation and stretching

Examine cellular responses to mechanical stress by indenting or stretching cells, and characterize their stiffness, elasticity, and viscosity.

Cell motility force dynamics

Quantify the forces involved in cell movement and analyze the dynamics of cell motility.

Molecular Biophysics

Phase Separation (LLPS)

Colloids & Soft Matter Physics

microtubules motor proteins mechanobiology application

Motor proteins & filaments

Study the activity of motor proteins and characterize the mechanical properties of microfilaments and microtubules in vitro and in vivo conditions.

Single-molecule application with optical tweezers

Single-molecule interactions

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LLPS of protein droplets application with optical tweezers

LLPS of condensates

Track changes in the mechanical properties of protein condensates over time by measuring their G modulus with our active rheology routines.

Colloids physics application with optical tweezers

Colloids and soft matter physics

Measure colloidal particles interactions and the rheological properties of colloids, gels, biofilms or liquid crystals. 

Molecular Biophysics

Motor proteins & filaments

Investigate motor protein activity and characterize the mechanical properties of microfilaments and microtubules under both in vitro and in vivo conditions.

Single-molecule interactions

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Phase Separation (LLPS)

LLPS of condensates

Monitor the evolving mechanical properties of protein condensates by measuring their G modulus using our active rheology techniques.

Colloids & Soft Matter Physics

Colloids and soft matter physics

Assess interactions among colloidal particles and measure the rheological properties of colloids, gels, biofilms, or liquid crystals.

Is your application not listed above? Write us and let’s see what we can do!